Posts of last 24 hours
当代人类的平均寿命约为 71 岁，有少数人能迎来百岁生日，而能活过 110 岁的人则更稀有，他们被称为“超级百岁老人”。根据发表在《Cell Reports》期刊上的一项研究，日本大阪大学研究团队发现，一种罕见的免疫细胞会随着极端高龄而显著增加。这类细胞兼具识别威胁和杀伤危险细胞的能力，或有助于超级百岁老人应对随着年龄增长而增加的持续性健康威胁。随着年龄增长，一些疾病的患病风险会增加，人体抵御感染的免疫能力也会逐渐减弱。T细胞是人体免疫系统的一类重要细胞，主要分为两类：辅助性T细胞负责协调免疫反应，杀伤性T细胞则负责清除受感染或癌变细胞。研究人员发现，超级百岁老人会积累一种不同寻常的“混合型”T细胞，即CD4细胞毒性T淋巴细胞（CD4 CTL）。这类罕见细胞同时具备识别威胁和摧毁危险细胞的能力。研究人员分析了不同年龄组人群的免疫细胞，包括70—90岁人群、百岁老人以及超级百岁老人。结果发现，在生命的大部分阶段，这类细胞始终十分少见，但在接近100岁时开始显著增加。在超级百岁老人中，CD4 CTL占血液中全部T细胞的比例接近1/5，而在较年轻的研究参与者中，这一比例仅约4%。进一步分析发现，部分CD4 CTL发生了明显的克隆扩增，即少数细胞不断复制，形成了数量庞大的同源细胞群。这一现象提示，这些细胞可能长期受到某些特定抗原的反复刺激，并在持续的免疫应答过程中不断增殖。研究人员还发现，超级百岁老人这类细胞所携带的部分T细胞受体，与癌症患者肿瘤组织中的T细胞受体高度相似，但这些超级百岁老人均无癌症病史。研究人员表示，这一发现提示，这些免疫细胞可能具有识别肿瘤细胞的能力，甚至可能在肿瘤尚未发展到临床可检测阶段时，就已对其产生免疫反应。这些发现意味着，极端高龄时期的免疫变化可能并非免疫系统单纯“衰老”和“耗竭”，而更像是免疫系统为适应长期健康生存而进行的一种重新组织。
https://www.solidot.org/story?sid=85157
A vulnerability has been found in Oracle Java SE 6u95/7u80/8u45 and classified as critical. Affected by this vulnerability is an unknown functionality. This manipulation causes Remote Code Execution.
This vulnerability is handled as CVE-2015-4748. The attack can be initiated remotely. There is not any exploit available.
The affected component should be upgraded.
https://vuldb.com/vuln/76682
A vulnerability has been found in Oracle Java SE 6u95/7u80/8u45 and classified as critical. This affects an unknown function of the component RMI. The manipulation leads to information disclosure.
This vulnerability is uniquely identified as CVE-2015-4733. The attack is possible to be carried out remotely. No exploit exists.
The affected component should be upgraded.
https://vuldb.com/vuln/76668
A vulnerability described as critical has been identified in Oracle Java SE 6u95/7u80/8u45. The impacted element is an unknown function of the component Library Handler. The manipulation results in information disclosure.
This vulnerability was named CVE-2015-2590. The attack may be performed from remote. In addition, an exploit is available.
Upgrading the affected component is recommended.
https://vuldb.com/vuln/76579
A vulnerability, which was classified as critical, was found in Oracle Java SE 6u95/7u80/8u45. The impacted element is an unknown function of the component Library Handler. Executing a manipulation can lead to Remote Code Execution.
This vulnerability is handled as CVE-2015-4732. The attack can be executed remotely. There is not any exploit available.
You should upgrade the affected component.
https://vuldb.com/vuln/76667
A vulnerability was found in Oracle Java SE 6u95/7u80/8u45 and classified as problematic. This affects an unknown function of the component JSSE. Executing a manipulation can lead to information disclosure.
This vulnerability is tracked as CVE-2015-2625. The attack can be launched remotely. No exploit exists.
It is suggested to upgrade the affected component.
https://vuldb.com/vuln/76613
A vulnerability was found in Oracle Java SE 6u95/7u80/8u45 and classified as problematic. Affected by this issue is some unknown functionality of the component JNDI. Such manipulation leads to denial of service.
This vulnerability is uniquely identified as CVE-2015-4749. The attack can be launched remotely. No exploit exists.
It is suggested to upgrade the affected component.
https://vuldb.com/vuln/76683
A vulnerability, which was classified as critical, has been found in Oracle Java SE 6u95/7u80/8u45. The affected element is an unknown function of the component JMX. Performing a manipulation results in information disclosure.
This vulnerability is known as CVE-2015-4731. Remote exploitation of the attack is possible. No exploit is available.
It is advisable to upgrade the affected component.
https://vuldb.com/vuln/76666
A vulnerability classified as problematic was found in Oracle Java SE 6u95/7u80/8u45. This issue affects some unknown processing of the component JMX. The manipulation results in information disclosure.
This vulnerability was named CVE-2015-2621. The attack may be performed from remote. There is no available exploit.
Upgrading the affected component is advised.
https://vuldb.com/vuln/76609
Flock 的车牌跟踪系统最近在美国引发了激烈争论，媒体同一时间报道了大量警官利用 Flock 摄像头跟踪女友/前女友、妻子/前妻的新闻。但在一片争论之中，皇帝最忠实的助手、西斯尊主达斯·维达则大肆赞美了 Flock。周三晚上加州圣地亚哥公共安全与宜居社区委员会会议（Public Safety and Livable Neighborhoods Committee Meeting）的公众评论期间，达斯·维达在台上说，“皇帝是 Flock 的粉丝，我们必须继续利用 Flock 技术，如此才能跟踪和监视那些叛军渣滓，看着他们从一个游乐场到另一个游乐场，从游乐场到游泳池，从游泳池到体育馆。因为我们都知道，Flock 摄像头不仅跟踪车牌；它们还跟踪孩子。它们在公园和体育馆里跟踪孩子，我们需要这个，我需要它来跟踪前女友。”
https://www.solidot.org/story?sid=85156